Immunology

What is autoimmune disease? Systemic lupus erythematosus

Sometimes a person’s immune system fails, which can cause severe consequences for the functioning of the entire body and lead to autoimmune diseases. We are talking about disorders in the immune system, which perceives its own tissues and organs as foreign elements, enemies, and doing everything possible for their injuries.

Possible causes of autoimmune diseases

It is unclear why the body suddenly begins so eager to destroy itself. Aggravating factors are stress, trauma, infectious disease, negative impacts of the external environment. For example, under the influence of ultraviolet radiation or radiation of molecules of the damaged tissues changes, and the immune system begins to perceive them as an alien that must be destroyed. The immune system can “get confused” when the pathogen has similarities with the cells of the body, then suffers a bacterium or a virus and a healthy cell.

Autoimmune diseases can result from certain gene mutations that are passed down to man by inheritance.

What is systemic lupus erythematosus?

One of the severe autoimmune diseases – systemic lupus erythematosus (SLE). A person suffering from this disease, the immune system starts fighting its own cells, perceiving them as strangers, dangerous. The vast majority of patients with lupus, 90% are women, the first symptoms of the disease appear at a young age – from 15 to 25 years.

In lupus the immune system damages the vital organs such as the heart, lungs, liver, kidneys, brain, and joints, skin, blood vessels.
The exact cause of SLE is unclear, but of great importance bad heredity in this matter. Factors that can trigger lupus, the following:

  • stress, strong emotional feelings;
  • childbirth, abortion;
  • prolonged exposure to the sun;
  • virus infection.

The development and symptoms of lupus

The disease develops gradually, first person just feels constant weakness, lose weight for no apparent reason, hurts his joints, occasionally the temperature rises. However, sometimes acute onset of illness, with inflammation of the skin, joints, fever.

Lupus develops in waves, every aggravation comes remission, and then peaking again with the defeat of new organs and tissues.

Visible symptoms of SLE include:

  • Redness of the nose and cheeks in a butterfly shape.
  • Rashes that resemble red rings with pale skin inside.
  • Redness of the skin of the neck and upper chest, which can stronger manifest when a person is anxious, is on the sun, wind, frost.
  • The defeat of the mucous membranes of the mouth and lips that resembles the canker.
  • Pain in the joints are symmetrical (knees, shoulders, wrists).
  • Pain in the muscles.

Complications of lupus is very severe, this inflammation of the peritoneum, pericardium, pleura, kidney, liver, heart, lungs, brain.

Treatment of lupus

Autoimmune disease to treat hard, treatment is aggressive, but necessary to save human life. For systemic lupus erythematosus treated by internists, rheumatologists and immunologists, and they need to work together. Naturally, the earlier the treatment starts, the higher the chances of any success.

Treatment of lupus includes anti-inflammatory medications hormonal nature, of the immunosuppressants. If the disease is aggressive, the patient shows a plasmapheresis (blood purification procedure).

Autoimmune disease is for life, it can only try to control. The patient requires constant medical supervision, because of the aggressive treatment may have adverse reactions to medications. Patients can sunbathe, you need to avoid hypothermia, vaccinations, they also are contraindicated. If a person was diagnosed with “systemic lupus erythematosus”, he should learn to keep your life under control.

Tags